We also developed various project to explore the new possibilities offered by our microniche approach.
In particular we use it to develop organoids with controlled boundary conditions to standardize their shape and development.
==> We collaborate with T. Dawson (Singapore) to create artificial hair follicles;
==> We collaborate with Ivo Lieberam (Kings College London) to create controllable neuromuscular contacts;
==> We collaborate with Yi-Chi Toh (Singapore) to create model for neurotube formation.
We started a bottom up project to understand how hepatocytes develop long secretory tubes between cell doublets (canaliculi) into which bile is secreted. These tube form between 2 cells then elongate to other cell-cell contacts by cord hollowing.